Circulation in profound hypothermia.

نویسندگان

  • C K Zarins
  • D B Skinner
چکیده

HIBERNATING MAMMALS MAINTAIN effective cardiac action and circulation at temperatures of 5OC for prolonged periods of time [13, 15, 191. Nonhibernatom, on the other hand, undergo cardiac failure and expire at low body temperatures unless rewarmed and resuscitated within a short time [3, 171. Artificial circulation with a pump oxygenator has improved the tolerance of profound hypothermia and dogs have survived long-term with no ill effects after 2 hr at a body temperature below 10% [17]. The effect of maintaining an intact pulsatile circulation in profound induced hypothermia has not previously been reported. A noninvasive pulsatile pumping system, mechanical ventricular assist (MVA) has been extensively studied as a technique for total circulatory support in normothermia [l, 23, 30, 321. The use of the MVA at low body temperatures provides mechanical cardiac function, lack of which is the initial and most obvious cause of circulatory failure. Dogs have been maintained for 2 hr with core temper-

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عنوان ژورنال:
  • The Journal of surgical research

دوره 14 2  شماره 

صفحات  -

تاریخ انتشار 1973